(1) Overview
Context
Spatial coverage
United Kingdom
Temporal coverage
2010-2012
Species
homo sapiens
(2) Methods
Steps
Systematic review: The systematic literature review included 115 published papers relevant to newborn screening for congenital hypothyroidism. Evidence summaries relating to each topic area were developed.
Expert Working Group: Members of the working group provided a consensus interpretation of the evidence relating to each standard. Recommendations for revising each standard were based on expert interpretation of the evidence and, if required, external experts were invited to present additional evidence.
Public consultation: A public consultation on the draft recommendations and revised standards was held in May/June 2012.
Published standards: A final revised set of standards was approved as screening policy and published in February 2013.
Sampling Strategy
Search strategies included the databases Embase, Medline, PsychInfo and Cochrane Trials Register, for the period up to June 2010, without imposing any language restrictions. Reference lists of retrieved papers were reviewed to identify additional papers.
Quality Control
Working Group recommendations were submitted to the UK National Screening Committee. A public consultation was held in May 2012. A publicly available consultation report is available from the UK Newborn Screening Programme.[1]
Constraints
N/A
Privacy
Working group members, and any additional experts consulted, are named and their affiliations provided in the appendix to the report.
(3) Dataset Description
Object Name
FINAL_REPORT_ICR_CHT_REVIEW_Jan 2013
Data Type
Grey literature
Format Names and Versions
PDF, ODT
Creation Dates
1st January 2013
Dataset Creators
Rachel L Knowles, Freyja Olafsdottir
Repository Location
Publication Date
January 2013
language
English
License
CC0
(4) Reuse potential
The systematic evidence review and report of the proceedings of the working group provides an evidence base for reviewing standards for clinical referral and investigation after newborn screening for CHT in the UK, but would also be of relevance to other populations undertaking newborn bloodspot screening. It describes a transparent process for agreeing changes to screening standards and policy that is based on achieving cross-disciplinary understanding and consensus, and actively includes parents. The report is available to users and is intended to support the development of communication and a transparent methodology for achieving consensus and collaboration around newborn screening policy.